L484 Pill (Acetaminophen 500 mg)

used to treat mild to moderate pain

temporarily relieves minor aches

popularly sold under the brand name Tylenol

In the realm of pain relief, the L484 pill, containing 500 mg of acetaminophen, is a popular choice for treating mild to moderate pain. Widely used for its effectiveness in reducing fever and soothing muscle aches, it’s crucial to understand its proper usage and potential risks. As with any medication, being informed about dosing instructions, possible interactions, and overdose symptoms is essential. Let’s delve deeper into the nuances of acetaminophen use and its significance in pain management.

What is the L484 Pill (Acetaminophen 500 mg)?

The L484 pill is an over-the-counter (OTC) painkiller containing 500 milligrams of acetaminophen as its active ingredient. It is a white, oval-shaped tablet with the imprint “L484” on one side. Acetaminophen is a widely used pain reliever and fever reducer in many popular brand-name medications.

L484 pills

Key points about the L484 pill:

  • Active Ingredient: Acetaminophen (500 mg)
  • Pill Imprint: L484
  • Use: Pain relief, fever reduction

L484 Pill Designation

The designation “L484” is an identifier that distinguishes this particular OTC medication from others. It helps pharmacists and consumers easily recognize and select the correct product from the shelf. The L484 marking is unique to this specific acetaminophen product.

Common Types of Acetaminophen

Acetaminophen is a common OTC medication available in various formulations and brand names. Here are some other types of acetaminophen products:

  • Tylenol: One of the most well-known brand names for acetaminophen, available in formulations such as extra strength, rapid release, and extended-release.
  • Panadol: Another brand of acetaminophen, available in different formulations and strengths, is used for pain relief and fever reduction.
  • Excedrin Tension Headache: Combines acetaminophen with caffeine to relieve tension headaches.
  • Nyquil: Some formulations of Nyquil, a popular cold and flu medication, contain acetaminophen and other active ingredients.
  • Dayquil: Similar to Nyquil, Dayquil is a daytime cold and flu medication that may contain acetaminophen.
  • Feverall: An acetaminophen suppository used for fever reduction in children and adults.

L484 Pill Dosage

The L484 pill typically contains 500 milligrams of acetaminophen to alleviate mild to moderate pain and reduce fever.

Dosage Guidelines:

Adult Dosage

  • The usual adult dosage of acetaminophen is 500 mg to 1000 mg every 4 to 6 hours as needed.
  • Adults’ recommended daily dose is typically 4000 mg (4 grams). It’s important not to exceed this limit to avoid the risk of liver damage.

Pediatric Dosage

  • The dosage is based on the weight of the children. Follow the recommendations provided by your healthcare provider or on the product label for appropriate dosing based on your child’s age and weight.


  • Acetaminophen can be taken with or without food.
  • Follow the specific dosing instructions provided on the product packaging or as directed by your healthcare provider.
  • Be cautious about using multiple medications that contain acetaminophen simultaneously to prevent accidental overdose. Acetaminophen is commonly found in various OTC products, such as cold and flu medications.
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Seek Medical Attention for Overdose Symptoms

If you suspect an overdose or experience symptoms such as nausea, vomiting, loss of appetite, confusion, or unusual tiredness, seek immediate medical attention.

Missed Dose

If you miss a dose of acetaminophen, take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double the dose to catch up.

How Long Does the L484 Pill Stay in Your System?

The L484 pill, containing acetaminophen, is primarily eliminated through the kidneys as an unchanged drug and its metabolites. In adults, the elimination half-life for acetaminophen is generally around 2 to 4 hours.

L484 Pill Onset and Duration

Acetaminophen’s onset of action is relatively quick, usually within 30 minutes to an hour after ingestion. The duration of action varies but is generally effective for about 4 to 6 hours.

Where Can I Purchase L484?

The L484 pill, a generic version of acetaminophen 500 mg, is widely available OTC at various locations, including:

  • Pharmacies: Local pharmacies, including chain pharmacies and independent drugstores.
  • Grocery Stores: Many grocery stores have a health and wellness section that includes OTC medications.
  • Online Retailers: You can purchase acetaminophen, including generic versions like L484, from various online retailers and pharmacy websites.
  • Big-Box Stores: Large retail stores and supercenters often have a pharmacy section.

L484 Pill Storage and Disposal


  • Keep acetaminophen (L484 pill) in its original packaging.
  • Store at room temperature, away from moisture and heat.
  • Avoid exposure to direct sunlight.
  • Keep the medication out of reach of children.


  • Follow local guidelines or regulations for medication disposal.
  • Do not flush acetaminophen down the toilet unless instructed to do so.
  • Consider using a drug take-back program if available.
  • Dispose of unused or expired medication to prevent accidental ingestion.

L484 Pill Uses to Relieve Pain

L484 pills are primarily used for:

  • Pain Relief: Effective for relieving mild to moderate pain, such as headaches, muscle aches, and toothaches.
  • Fever Reduction: Helps reduce fever, making it suitable for managing flu and cold symptoms.
  • Common Uses: Alleviates mild to moderate pain from headaches, muscle aches, toothaches, and menstrual cramps and reduces fever.

L484 Pill Efficacy

Acetaminophen is known for its efficacy in managing mild to moderate pain and fever in various conditions.

Efficacy of Acetaminophen (L484 pill):

  • Pain Relief: Effective for headaches, muscle aches, toothaches, and menstrual cramps.
  • Fever Reduction: Commonly used to reduce fever associated with infections or other medical conditions.
  • Arthritis Pain: Often used to alleviate pain associated with arthritis, although NSAIDs are also commonly prescribed for this purpose.
  • General Pain Management: Widely used and effective for general pain management, considered a first-line option for specific conditions.

How L484 Works

The active ingredient, acetaminophen, works by inhibiting certain chemicals in the brain that transmit pain signals and regulate body temperature. While its exact mechanism of action is not fully understood, it is believed to involve:

  • Inhibition of Prostaglandin Synthesis: Reduces the production of prostaglandins in the central nervous system, helping alleviate pain and lower fever.
  • Action in the Central Nervous System: Targets the hypothalamus, which regulates temperature.
  • Limited Peripheral Effects: This does not significantly inhibit the activity of cyclooxygenase (COX) enzymes outside the central nervous system.

How Does L484 Pill Work on the Brain and Body?

Acetaminophen, the active ingredient in medications like the L484 pill, works primarily in the central nervous system to alleviate pain and reduce fever. It is thought to inhibit the production of prostaglandins in the brain, which are involved in pain perception and temperature regulation. Unlike NSAIDs, acetaminophen does not have significant anti-inflammatory effects.

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Side Effects and Risks of the L484 Pill

Acetaminophen is generally considered safe when used as directed. However, short-term and long-term use can be associated with specific side effects.

Short-Term Side Effects:

  • Nausea and Vomiting: Some individuals may experience mild gastrointestinal upset.
  • Allergic Reactions: Rare but possible, leading to symptoms such as rash, itching, or swelling.
  • Liver Damage (Overdose): Excessive doses can lead to severe liver damage, requiring immediate medical attention.

Long-Term Side Effects:

  • Liver Damage: Prolonged use at high doses may lead to chronic liver damage.
  • Kidney Damage: Rare but possible with long-term, high-dose use.
  • Blood Disorders: Rare reports associated with long-term, high-dose use.
  • Gastrointestinal Issues: Although gentler on the stomach than NSAIDs, high doses may contribute to gastrointestinal issues.

Is the L484 Pill Addictive?

No, the L484 pill, which contains acetaminophen, is not addictive. Acetaminophen is not classified as an addictive substance and does not produce the euphoric or psychoactive effects typically associated with addictive drugs.

Can You Overdose on L484? Recognizing Overdose Symptoms

Yes, it is possible to overdose on medications containing acetaminophen, including those with the L484 imprint. Acetaminophen overdose can lead to severe liver damage, which can be life-threatening. The maximum recommended daily dose for adults is typically around 4,000 milligrams. Exceeding this limit increases the risk of overdose.

Symptoms of Acetaminophen overdose may include:

  • Nausea or vomiting
  • Loss of appetite
  • Confusion
  • Jaundice (yellowing of the skin or eyes)
  • Unusual tiredness or weakness
  • Severe abdominal pain

If you suspect an overdose or experience symptoms of acetaminophen toxicity, seek emergency medical attention or contact your local poison control center.

L484 Pill and Alcohol Use

Combining acetaminophen with alcohol can pose significant risks and is not recommended.

  • Liver Damage: Both substances are metabolized in the liver, increasing the risk of liver damage.
  • Increased Toxicity: Combining acetaminophen with alcohol may increase the likelihood of an overdose.
  • Gastrointestinal Effects: Both substances can irritate the stomach lining, leading to gastrointestinal side effects.
  • Impaired Judgment: Alcohol can impair judgment, potentially leading to unintentional acetaminophen overdose.

L484 Pill and Pregnancy

L484 Pill and Pregnancy

Acetaminophen is generally considered safe for use during pregnancy, particularly during the first and second trimesters. However, it’s essential to consider the following:

  • Risk of Birth Defects: Limited evidence suggests a slightly increased risk of certain birth defects with higher doses or prolonged use.
  • Risk of Preterm Birth: Some studies suggest a potential link to preterm birth or low birth weight, although the overall risk is low.
  • Consultation with Healthcare Provider: Consult with your healthcare provider before taking acetaminophen during pregnancy.

L484 Pill Interaction With Other Medications

While acetaminophen is generally safe, it’s essential to be aware of potential interactions with other medications:

  • Blood Thinners: This may increase the risk of bleeding.
  • Alcohol: Increases the risk of liver damage.
  • Other Pain Relievers (NSAIDs) May increase the risk of gastrointestinal bleeding or kidney damage.
  • Medications Metabolized by the Liver: This may affect the metabolism and effectiveness of certain medications.
  • Certain Health Conditions: Use caution in individuals with liver disease or impaired liver function.

Safety Precautions for L484 Pill Use in Patients with Liver Disease

While L484 pills are readily available without a prescription, it’s essential to use them responsibly:

  • Dosage: Follow the recommended dosage instructions.
  • Avoid Alcohol: Refrain from or restrict alcohol intake when using acetaminophen.
  • Consult a Healthcare Professional: If you have liver disease, talk to a healthcare provider before using L484.
  • Keep Out of Reach of Children: Store these pills safely.

While the L484 pill offers relief from various types of discomfort, it’s paramount to use it responsibly. Always adhere to recommended doses, avoid combining them with other medications without consulting a healthcare provider, and be vigilant about potential signs of acetaminophen overdose. Whether treating mild to moderate pain or reducing fever, seeking medical attention for any concerning symptoms is imperative. By prioritizing proper usage and staying informed, individuals can effectively harness the benefits of acetaminophen while minimizing associated risks.


Can I take L484 with other medications?

It is crucial to consult a healthcare professional before combining L484 with other medications to avoid potential drug interactions.

How often can I take L484 for pain relief?

Follow the dosing instructions on the packaging. Typically, L484 can be taken every 4-6 hours as needed for pain relief.

Is L484 safe for children?

L484 is not recommended for children under 12 without consulting a healthcare provider.

What should I do if I accidentally take too much L484?

If you suspect an overdose, seek medical attention immediately, as it can lead to serious health complications.

Can I drive or operate machinery after taking L484?

L484 is not known to cause drowsiness, but individual reactions may vary. Exercise caution until you know how it affects you.

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Alex Koliada, PhD

Alex Koliada, PhD

Alex Koliada, PhD, is a well-known doctor. He is famous for his studies of ageing, genetics and other medical conditions. He works at the Institute of Food Biotechnology and Genomics NAS of Ukraine. His scientific researches are printed by the most reputable international magazines. Some of his works are: Differences in the gut Firmicutes to Bacteroidetes ratio across age groups in healthy Ukrainian population [BiomedCentral.com]; Mating status affects Drosophila lifespan, metabolism and antioxidant system [Science Direct]; Anise Hyssop Agastache foeniculum Increases Lifespan, Stress Resistance, and Metabolism by Affecting Free Radical Processes in Drosophila [Frontiersin].
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